CCR7/p-ERK1/2/VEGF signaling promotes retinal neovascularization in a mouse model of oxygen-induced retinopathy

AIM: To investigate the role of CCR7/p-ERK1/2/VEGF signaling in the mouse model of oxygen-induced retinopathy (OIR). METHODS: Neonatal C57BL/6J mice were evenly randomized into four groups: normoxia, OIR, OIR control (treated with scramble siRNA), and OIR treated (treated with CCR7 siRNA). Normoxia...

Full description

Bibliographic Details
Main Authors: Lin-Hui Yuan, Xiao-Long Chen, Yu Di, Mei-Lin Liu
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2017-06-01
Series:International Journal of Ophthalmology
Subjects:
869
Online Access:http://www.ijo.cn/en_publish/2017/6/20170606.pdf