The Wilms' tumor suppressor gene regulates pancreas homeostasis and repair.

The Wilms' tumor suppressor gene (Wt1) encodes a zinc finger transcription factor that plays an essential role in the development of kidneys, gonads, spleen, adrenals and heart. Recent findings suggest that WT1 could also be playing physiological roles in adults. Systemic deletion of WT1 in mic...

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Bibliographic Details
Main Authors: Laura Ariza, Anabel Rojas, Ramón Muñoz-Chápuli, Rita Carmona
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC6392337?pdf=render