Paclitaxel May Inhibit Epithelial-Mesenchymal Transition Properties of Triple-negative Breast Cancer Cell Line via Altering the Expression of EMT-promoting and –inhibiting MicroRNAs

Paclitaxel May Inhibit Epithelial-Mesenchymal Transition Properties of Triple-negative Breast Cancer Cell Line via Altering the Expression of EMT-promoting and –inhibiting MicroRNAs

Background: Abnormal expressions of microRNAs are related to various cancers such as breast cancer for which paclitaxel is widely used as a chemotherapeutic agent. We aimed to investigate the effect of paclitaxel treatment on the expression level of miR-199a-5p and miR-10b, involved in epithelial-me...

Full description

Bibliographic Details
Main Authors: Navideh Haghnavaz, Faezeh Asghari, Najibeh Shekari, Dariush Shanehbandi, Mahsa Javadian, Ali Mohammadi, Behzad Baradaran, Tohid Kazemi
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2020-01-01
Series:Middle East Journal of Cancer
Subjects:
breast cancer
mir-199a-5p
mir-10b
paclitaxel
vimentin
mmp-9
Online Access:http://mejc.sums.ac.ir/article_45951.html

Internet

http://mejc.sums.ac.ir/article_45951.html

Similar Items