Neuroprotective effects of irisin against cerebral ischemia/ reperfusion injury via Notch signaling pathway

Irisin, a 112-amino acid peptide induced with exercise in mice and human is thought to have correlation with the short-term outcomes of patients in ischemic stroke. In the present study, the neuroprotective effects of irisin were evaluated in vivo and in vitro and its underlying mechanism was also e...

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Bibliographic Details
Main Authors: Zhao Jin, Peipei Guo, Xinyi Li, Jianjuan Ke, Yanlin Wang, Huisheng Wu
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219339447