When human guanylate-binding proteins meet viral infections

Abstract Innate immunity is the first line of host defense against viral infection. After invading into the cells, pathogen-associated-molecular-patterns derived from viruses are recognized by pattern recognition receptors to activate the downstream signaling pathways to induce the production of typ...

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Bibliographic Details
Main Authors: Rongzhao Zhang, Zhixin Li, Yan-Dong Tang, Chenhe Su, Chunfu Zheng
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Journal of Biomedical Science
Subjects:
Online Access:https://doi.org/10.1186/s12929-021-00716-8