Structures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction

Structures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction

Teneurins are cell-cell adhesion receptors that evolved through horizontal gene transfer in which a bacterial YD-repeat protein fused to a eukaryotic receptor. Here the authors present crystallographic and cryo-EM structures of two Teneurins, revealing an ancient YD-repeat protein super-fold.

Bibliographic Details
Main Authors: Verity A. Jackson, Dimphna H. Meijer, Maria Carrasquero, Laura S. van Bezouwen, Edward D. Lowe, Colin Kleanthous, Bert J. C. Janssen, Elena Seiradake
Format: Article
Language:English
Published: Nature Publishing Group 2018-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-03460-0

Internet

https://doi.org/10.1038/s41467-018-03460-0

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