Improving the Production of Riboflavin by Introducing a Mutant Ribulose 5-Phosphate 3-Epimerase Gene in Bacillus subtilis

Improving the Production of Riboflavin by Introducing a Mutant Ribulose 5-Phosphate 3-Epimerase Gene in Bacillus subtilis

Ribulose 5-phosphate (Ru5P) and guanosine 5′-triphosphate (GTP) are two key precursors of riboflavin, whereby Ru5P is also a precursor of GTP. Ribulose 5-phosphate 3-epimerase (Rpe) catalyzes the conversion of ribulose 5-phosphate into xylulose 5-phosphate. Inactivation of Rpe can reduce the consump...

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Bibliographic Details
Main Authors: Bin Yang, Yiwen Sun, Shouying Fu, Miaomiao Xia, Yuan Su, Chuan Liu, Chunzhi Zhang, Dawei Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
riboflavin
ribulose 5-phosphate 3-epimerase
pentose phosphate pathway
truncated protein
Bacillus subtilis
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.704650/full

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https://www.frontiersin.org/articles/10.3389/fbioe.2021.704650/full

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