The Effect of Mipomersen in the Management of Patients with Familial Hypercholesterolemia: A Systematic Review and Meta-Analysis of Clinical Trials

<b>Background:</b> Familial hypercholesterolemia (FH) lead to significant adverse effects in coronary arteries. Mipomersen is a second-generation antisense oligonucleotide that inhibits the synthesis of apolipoprotein B-100, an essential component of low density lipoprotein (LDL), and th...

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Bibliographic Details
Main Authors: Behrooz Astaneh, Nima Makhdami, Vala Astaneh, Gordon Guyatt
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
Online Access:https://www.mdpi.com/2308-3425/8/7/82