The Effect of Mipomersen in the Management of Patients with Familial Hypercholesterolemia: A Systematic Review and Meta-Analysis of Clinical Trials
<b>Background:</b> Familial hypercholesterolemia (FH) lead to significant adverse effects in coronary arteries. Mipomersen is a second-generation antisense oligonucleotide that inhibits the synthesis of apolipoprotein B-100, an essential component of low density lipoprotein (LDL), and th...
Main Authors: | Behrooz Astaneh, Nima Makhdami, Vala Astaneh, Gordon Guyatt |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-07-01
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Series: | Journal of Cardiovascular Development and Disease |
Subjects: | |
Online Access: | https://www.mdpi.com/2308-3425/8/7/82 |
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