Immediate and durable effects of maternal tobacco consumption alter placental DNA methylation in enhancer and imprinted gene-containing regions

Immediate and durable effects of maternal tobacco consumption alter placental DNA methylation in enhancer and imprinted gene-containing regions

Abstract Background Although exposure to cigarette smoking during pregnancy has been associated with alterations of DNA methylation in the cord blood or placental cells, whether such exposure before pregnancy could induce epigenetic alterations in the placenta of former smokers has never been invest...

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Bibliographic Details
Main Authors: Sophie Rousseaux, Emie Seyve, Florent Chuffart, Ekaterina Bourova-Flin, Meriem Benmerad, Marie-Aline Charles, Anne Forhan, Barbara Heude, Valérie Siroux, Remy Slama, Jorg Tost, Daniel Vaiman, Saadi Khochbin, Johanna Lepeule, the EDEN Mother-Child Cohort Study Group
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Medicine
Subjects:
Placenta
DNA methylation
Pregnancy
Smoking
Epigenome-wide association study
Molecular epidemiology
Online Access:http://link.springer.com/article/10.1186/s12916-020-01736-1

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http://link.springer.com/article/10.1186/s12916-020-01736-1

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