Nanoscale 3D EM reconstructions reveal intrinsic mechanisms of structural diversity of chemical synapses

Nanoscale 3D EM reconstructions reveal intrinsic mechanisms of structural diversity of chemical synapses

Summary: Chemical synapses of shared cellular origins have remarkably heterogeneous structures, but how this diversity is generated is unclear. Here, we use three-dimensional (3D) electron microscopy and artificial intelligence algorithms for image processing to reconstruct functional excitatory mic...

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Bibliographic Details
Main Authors: Yongchuan Zhu, Marco Uytiepo, Eric Bushong, Matthias Haberl, Elizabeth Beutter, Frederieke Scheiwe, Weiheng Zhang, Lyanne Chang, Danielle Luu, Brandon Chui, Mark Ellisman, Anton Maximov
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Cell Reports
Subjects:
neuron
circuit
wiring
synapse
spine
diversity
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721002679

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http://www.sciencedirect.com/science/article/pii/S2211124721002679

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