Caspase-1 deficiency in mice reduces intestinal triglyceride absorption and hepatic triglyceride secretion[S]
Caspase-1 is known to activate the proinflammatory cytokines IL-1β and IL-18. Additionally, it can cleave other substrates, including proteins involved in metabolism. Recently, we showed that caspase-1 deficiency in mice strongly reduces high-fat diet-induced weight gain, at least partly caused by a...
Main Authors: | Janna A. van Diepen, Rinke Stienstra, Irene O. C.M. Vroegrijk, Sjoerd A.A. van den Berg, Daniela Salvatori, Guido J. Hooiveld, Sander Kersten, Cees J. Tack, Mihai G. Netea, Johannes W.A. Smit, Leo A.B. Joosten, Louis M. Havekes, Ko Willems van Dijk, Patrick C.N. Rensen |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2013-02-01
|
Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520428093 |
Similar Items
-
Brown adipose tissue takes up plasma triglycerides mostly after lipolysis
by: Padmini P.S.J. Khedoe, et al.
Published: (2015-01-01) -
Plasma apolipoprotein AV levels in mice are positively associated with plasma triglyceride levels
by: S.F.C. Vaessen, et al.
Published: (2009-05-01) -
Effects of cold exposure on heart clearing factor lipase and triglyceride utilization in the rat
by: M. Perenna Rogers, et al.
Published: (1974-05-01) -
Aging and plasma triglyceride metabolism
by: Kathryn M. Spitler, et al.
Published: (2020-08-01) -
Obstructive sleep apnea and effects of continuous positive airway pressure on triglyceride-rich lipoprotein metabolism[S]
by: Luciano F. Drager, et al.
Published: (2018-01-01)