Changes in protein expression in two cholangiocarcinoma cell lines undergoing formation of multicellular tumor spheroids in vitro.

Epithelial-to-Mesenchymal Transition (EMT) is relevant in malignant growth and frequently correlates with worsening disease progression due to its implications in metastases and resistance to therapeutic interventions. Although EMT is known to occur in several types of solid tumors, the information...

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Main Authors: Carlo Mischiati, Blendi Ura, Leda Roncoroni, Luca Elli, Carlo Cervellati, Monica Squerzanti, Dario Conte, Luisa Doneda, Patrizia Polverino de Laureto, Giorgia de Franceschi, Roberta Calza, Carlos A Barrero, Salim Merali, Carlo Ferrari, Carlo M Bergamini, Enzo Agostinelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4355290?pdf=render