Optimized metabolomic approach to identify uremic solutes in plasma of stage 3-4 chronic kidney disease patients.

Optimized metabolomic approach to identify uremic solutes in plasma of stage 3-4 chronic kidney disease patients.

BACKGROUND: Chronic kidney disease (CKD) is characterized by the progressive accumulation of various potential toxic solutes. Furthermore, uremic plasma is a complex mixture hampering accurate determination of uremic toxin levels and the identification of novel uremic solutes. METHODS: In this study...

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Bibliographic Details
Main Authors: Henricus A M Mutsaers, Udo F H Engelke, Martijn J G Wilmer, Jack F M Wetzels, Ron A Wevers, Lambertus P van den Heuvel, Joost G Hoenderop, Rosalinde Masereeuw
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3732267?pdf=render

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http://europepmc.org/articles/PMC3732267?pdf=render

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