NPT-IIb Inhibition Does Not Improve Hyperphosphatemia in CKD

NPT-IIb Inhibition Does Not Improve Hyperphosphatemia in CKD

Serum phosphate levels are insufficiently controlled in many patients with end-stage renal disease (ESRD), and novel therapeutic strategies are needed. Blocking intestinal phosphate absorption mediated by sodium-dependent phosphate co-transporter type 2b (NPT-IIb) holds promise; thus, we evaluated t...

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Bibliographic Details
Main Authors: Tobias E. Larsson, Chisato Kameoka, Ikumi Nakajo, Yuta Taniuchi, Satoshi Yoshida, Tadao Akizawa, Ronald A. Smulders
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Kidney International Reports
Subjects:
end-stage renal disease
hemodialysis
hyperphosphatemia
NPT-IIb inhibitor
pharmacokinetics
phase 1 trial
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024917303455

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http://www.sciencedirect.com/science/article/pii/S2468024917303455

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