NK cell mediated antibody-dependent cellular cytotoxicity in cancer immunotherapy

Natural killer (NK) cells play a major role in cancer immunotherapies that involve tumor-antigen targeting by monoclonal antibodies (mAbs). NK cells express a variety of activating and inhibitory receptors that serve to regulate the function and activity of the cells. In the context of targeting cel...

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Bibliographic Details
Main Authors: Wei eWang, Amy K. Erbe, Jacquelyn A. Hank, Zachary S. Morris, Paul Mark Sondel
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00368/full