Japanese Encephalitis Virus Vaccination Elicits Cross-Reactive HLA-Class I-Restricted CD8 T Cell Response Against Zika Virus Infection

Japanese Encephalitis Virus Vaccination Elicits Cross-Reactive HLA-Class I-Restricted CD8 T Cell Response Against Zika Virus Infection

Japanese encephalitis virus (JEV) exposure or vaccination could elicit cross-reactive CD8 T cell immunity against heterologous flaviviruses in humans. In addition, cross-reactive CD8 T cells induced by dengue virus (DENV) have been shown to play a protective role against Zika virus (ZIKV). However,...

Full description

Bibliographic Details
Main Authors: Marion Tarbe, Wei Dong, Guang Hu, Yongfen Xu, Jing Sun, Solene Grayo, Xianyang Chen, Chengfeng Qin, Jincun Zhao, Li Liu, Xiuzhen Li, Qibin Leng
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
JEV
Zika
cross-reactive
epitope
CD8 T cells
HLA-A2 transgenic mice
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.577546/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.577546/full

Similar Items