Whole-genome mutational burden analysis of three pluripotency induction methods

Whole-genome mutational burden analysis of three pluripotency induction methods

It is feared that reprogramming may introduce DNA mutations. Here Bhutani et al. take three different reprogramming methods and using comparative whole genome analyses do identify nucleotide variations that are different in reprogrammed cells from the original fibroblasts, but none convey oncogenic...

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Bibliographic Details
Main Authors: Kunal Bhutani, Kristopher L. Nazor, Roy Williams, Ha Tran, Heng Dai, Željko Džakula, Edward H. Cho, Andy W. C. Pang, Mahendra Rao, Han Cao, Nicholas J. Schork, Jeanne F. Loring
Format: Article
Language:English
Published: Nature Publishing Group 2016-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms10536

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https://doi.org/10.1038/ncomms10536

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