Comprehensive analysis of liver and blood miRNA in precancerous conditions

Comprehensive analysis of liver and blood miRNA in precancerous conditions

Abstract Streptozotocin administration to mice (STZ-mice) induces type I diabetes and hepatocellular carcinoma (HCC). We attempted to elucidate the carcinogenic mechanism and the miRNA expression status in the liver and blood during the precancerous state. Serum and liver tissues were collected from...

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Main Authors: Tomohiro Umezu, Koichi Tsuneyama, Kohsuke Kanekura, Michiyo Hayakawa, Toshihito Tanahashi, Mitsuoki Kawano, Y-h Taguchi, Hidenori Toyoda, Akihiro Tamori, Masahiko Kuroda, Yoshiki Murakami
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-78500-1

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https://doi.org/10.1038/s41598-020-78500-1

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