Retrieval of the Alzheimer's amyloid precursor protein from the endosome to the TGN is S655 phosphorylation state-dependent and retromer-mediated

Retrieval of the Alzheimer's amyloid precursor protein from the endosome to the TGN is S655 phosphorylation state-dependent and retromer-mediated

<p>Abstract</p> <p>Background</p> <p>Retrograde transport of several transmembrane proteins from endosomes to the trans-Golgi network (TGN) occurs via Rab 5-containing endosomes, mediated by clathrin and the recently characterized retromer complex. This complex and one...

Full description

Bibliographic Details
Main Authors: Gandy Sam, Small Scott A, Lane Rachel, Lah James, Wiltfang Jens, Esselmann Hermann, Rebelo Sandra, Vieira Sandra I, da Cruz e Silva Edgar F, da Cruz e Silva Odete AB
Format: Article
Language:English
Published: BMC 2010-10-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/5/1/40

Internet

http://www.molecularneurodegeneration.com/content/5/1/40

Similar Items