In vitro Activity of Apramycin Against Carbapenem-Resistant and Hypervirulent Klebsiella pneumoniae Isolates

ObjectiveThe emergence of carbapenem-resistant and hypervirulent Klebsiella pneumoniae (CR-hvKp) strains poses a significant public threat, and effective antimicrobial therapy is urgently needed. Recent studies indicated that apramycin is a potent antibiotic with good activity against a range of mul...

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Bibliographic Details
Main Authors: Mingju Hao, Xiaohong Shi, Jingnan Lv, Siqiang Niu, Shiqing Cheng, Hong Du, Fangyou Yu, Yi-Wei Tang, Barry N. Kreiswirth, Haifang Zhang, Liang Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00425/full