Amniotic fluid stem cells ameliorate cisplatin-induced acute renal failure through induction of autophagy and inhibition of apoptosis

Amniotic fluid stem cells ameliorate cisplatin-induced acute renal failure through induction of autophagy and inhibition of apoptosis

Abstract Background We have recently demonstrated that amniotic fluid stem cells (AFSC) express renal progenitor markers and can be differentiated in vitro into renal lineage cell types, viz, juxtaglomerular and renal proximal tubular epithelial-like cells. Here, we have evaluated the therapeutic ef...

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Bibliographic Details
Main Authors: Ekta Minocha, Rohit Anthony Sinha, Manali Jain, Chandra Prakash Chaturvedi, Soniya Nityanand
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Stem Cell Research & Therapy
Subjects:
Amniotic fluid stem cells
Cisplatin
Acute renal failure
Apoptosis
Autophagy
Chloroquine
Online Access:https://doi.org/10.1186/s13287-019-1476-6

Internet

https://doi.org/10.1186/s13287-019-1476-6

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