Prediction of Drug Stability Using Deep Learning Approach: Case Study of Esomeprazole 40 mg Freeze-Dried Powder for Solution

Prediction of Drug Stability Using Deep Learning Approach: Case Study of Esomeprazole 40 mg Freeze-Dried Powder for Solution

A critical step in the production of Esomeprazole powder for solution is a period between the filling process and lyophilization, where all vials, partially closed, are completely exposed to environmental influences. Excessive instability reflects in pH value variations caused by oxygen’s impact. In...

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Bibliographic Details
Main Authors: Jovana Ajdarić, Svetlana Ibrić, Aleksandar Pavlović, Ljubiša Ignjatović, Branka Ivković
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Pharmaceutics
Subjects:
esomeprazole sodium
stability
deep learning
multilayer perceptron
artificial neural network
freeze-drying
Online Access:https://www.mdpi.com/1999-4923/13/6/829

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https://www.mdpi.com/1999-4923/13/6/829

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