Iron labeling and pre-clinical MRI visualization of therapeutic human neural stem cells in a murine glioma model.

Treatment strategies for the highly invasive brain tumor, glioblastoma multiforme, require that cells which have invaded into the surrounding brain be specifically targeted. The inherent tumor-tropism of neural stem cells (NSCs) to primary and invasive tumor foci can be exploited to deliver therapeu...

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Bibliographic Details
Main Authors: Mya S Thu, Joseph Najbauer, Stephen E Kendall, Ira Harutyunyan, Nicole Sangalang, Margarita Gutova, Marianne Z Metz, Elizabeth Garcia, Richard T Frank, Seung U Kim, Rex A Moats, Karen S Aboody
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2746284?pdf=render