Si-Miao-Yong-An decoction preserves cardiac function and regulates GLC/AMPK/NF-κB and GLC/PPARα/PGC-1α pathways in diabetic mice

Si-Miao-Yong-An decoction preserves cardiac function and regulates GLC/AMPK/NF-κB and GLC/PPARα/PGC-1α pathways in diabetic mice

Background: Diabetic cardiomyopathy (DCM) is a main cause of heart failure and death in diabetic patients. However, countermeasures to limit the development of this disease remain insufficient. Si-Miao-Yong-An decoction (SMYA), a Chinese herbal prescription, exhibits both lipid-lowering and cardiova...

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Bibliographic Details
Main Authors: Lin Li, Xiangyang Chen, Congping Su, Qing Wang, Rui Li, Wenchao Jiao, Hui Luo, Yimiao Tian, Jiayang Tang, Xiaoxuan Li, Bin Liu, Wei Wang, Dongwei Zhang, Shuzhen Guo
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Diabetic cardiomyopathy
Si-Miao-Yong-An decoction
Glucagon
AMPK/NF-κB
PPARα/PGC-1α
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220310106

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http://www.sciencedirect.com/science/article/pii/S0753332220310106

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