Facile Tumor Spheroids Formation in Large Quantity with Controllable Size and High Uniformity

Abstract A facile method for generation of tumor spheroids in large quantity with controllable size and high uniformity is presented. HCT-116 cells are used as a model cell line. Individual tumor cells are sparsely seeded onto petri-dishes. After a few days of growth, separated cellular islets are f...

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Bibliographic Details
Main Authors: Wentao Shi, Jean Kwon, Yongyang Huang, Jifu Tan, Christopher G. Uhl, Ran He, Chao Zhou, Yaling Liu
Format: Article
Language:English
Published: Nature Publishing Group 2018-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-25203-3