Cyclin-dependent kinase control of motile ciliogenesis

Cyclin-dependent kinase control of motile ciliogenesis

Cycling cells maintain centriole number at precisely two per cell in part by limiting their duplication to S phase under the control of the cell cycle machinery. In contrast, postmitotic multiciliated cells (MCCs) uncouple centriole assembly from cell cycle progression and produce hundreds of centri...

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Bibliographic Details
Main Authors: Eszter K Vladar, Miranda B Stratton, Maxwell L Saal, Glicella Salazar-De Simone, Xiangyuan Wang, Debra Wolgemuth, Tim Stearns, Jeffrey D Axelrod
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-08-01
Series:eLife
Subjects:
cilia
ciliogenesis
centriole
cell cycle
Cdk2
Cyclin A1
Online Access:https://elifesciences.org/articles/36375

Internet

https://elifesciences.org/articles/36375

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