The SCO4117 ECF Sigma Factor Pleiotropically Controls Secondary Metabolism and Morphogenesis in Streptomyces coelicolor

The SCO4117 ECF Sigma Factor Pleiotropically Controls Secondary Metabolism and Morphogenesis in Streptomyces coelicolor

Extracytoplasmic function (ECF) sigma factors are a major type of bacterial signal-transducers whose biological functions remain poorly characterized in streptomycetes. In this work we studied SCO4117, a conserved ECF sigma factor from the ECF52 family overexpressed during substrate and aerial mycel...

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Bibliographic Details
Main Authors: María T. López-García, Paula Yagüe, Nathaly González-Quiñónez, Beatriz Rioseras, Angel Manteca
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Microbiology
Subjects:
Streptomyces
ECF
sigma factor
differentiation
secondary metabolism
antibiotic
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2018.00312/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2018.00312/full

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