Exploration for novel inhibitors showing back-to-front approach against VEGFR-2 kinase domain (4AG8) employing molecular docking mechanism and molecular dynamics simulations

Abstract Background Angiogenesis is a process of formation of new blood vessels and is an important criteria demonstrated by cancer cells. Over a period of time, these cancer cells infect the other parts of the healthy body by a process called progression. The objective of the present article is to...

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Bibliographic Details
Main Authors: Shailima Rampogu, Ayoung Baek, Amir Zeb, Keun Woo Lee
Format: Article
Language:English
Published: BMC 2018-03-01
Series:BMC Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12885-018-4050-1