Multifunctional Nanodrug Mediates Synergistic Photodynamic Therapy and MDSCs‐Targeting Immunotherapy of Colon Cancer

Multifunctional Nanodrug Mediates Synergistic Photodynamic Therapy and MDSCs‐Targeting Immunotherapy of Colon Cancer

Abstract An ideal tumor treatment is supposed to eliminate the primary tumor and simultaneously trigger the host antitumor immune responses to prevent tumor recurrence and metastasis. Herein, a liposome encapsulating phosphoinositide 3‐kinase gamma (PI3Kγ) inhibitor IPI‐549 and photosensitizer chlor...

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Bibliographic Details
Main Authors: Dongbing Ding, Huihai Zhong, Rongpu Liang, Tianyun Lan, Xudong Zhu, Shengxin Huang, Yong Wang, Jun Shao, Xintao Shuai, Bo Wei
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:Advanced Science
Subjects:
immunotherapy
myeloid‐derived suppressive cells (MDSCs)
multifunctional nanodrug
photodynamic therapy
PI3Kγ inhibitor
Online Access:https://doi.org/10.1002/advs.202100712

Internet

https://doi.org/10.1002/advs.202100712

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