AMPK Activation Promotes Tight Junction Assembly in Intestinal Epithelial Caco-2 Cells

AMPK Activation Promotes Tight Junction Assembly in Intestinal Epithelial Caco-2 Cells

The AMP-activated protein kinase (AMPK) is principally known as a major regulator of cellular energy status, but it has been recently shown to play a key structural role in cell-cell junctions. The aim of this study was to evaluate the impact of AMPK activation on the reassembly of tight junctions i...

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Bibliographic Details
Main Authors: Séverine Olivier, Jocelyne Leclerc, Adrien Grenier, Marc Foretz, Jérôme Tamburini, Benoit Viollet
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
ampk
direct ampk activator
calcium switch
caco-2 cells
intestinal barrier function
tight junction
trans-epithelial electrical resistance
paracellular permeability
Online Access:https://www.mdpi.com/1422-0067/20/20/5171

Internet

https://www.mdpi.com/1422-0067/20/20/5171

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