ZDOG: zooming in on dominating genes with mutations in cancer pathways

Abstract Background Inference of cancer-causing genes and their biological functions are crucial but challenging due to the heterogeneity of somatic mutations. The heterogeneity of somatic mutations reveals that only a handful of oncogenes mutate frequently and a number of cancer-causing genes mutat...

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Bibliographic Details
Main Authors: Rudi Alberts, Jinyu Chen, Louxin Zhang
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-019-3326-z