Immunosuppressive Siglec-E ligands on mouse aorta are up-regulated by LPS via NF-κB pathway

Immunosuppressive Siglec-E ligands on mouse aorta are up-regulated by LPS via NF-κB pathway

Aims: Siglec-E, the mouse ortholog of human Siglec-9, is an immunosuppressive cell surface receptor. Both Siglec-E and Siglec-9 are primarily found on neutrophils, macrophages, and monocytes. When Siglec-E binds to sialoglycan ligands in its extracellular environment, it halts the immune cells’ infl...

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Bibliographic Details
Main Authors: Hongmei Liu, Yu Zheng, Yingxian Zhang, Jin Li, Steve M. Fernandes, Dongfeng Zeng, Xiaohui Li, Ronald L. Schnaar, Yi Jia
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Siglec-E ligands
Endothelial cells
LPS
Deleted in malignant brain tumors-1
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S075333221935382X

Internet

http://www.sciencedirect.com/science/article/pii/S075333221935382X

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