Engineering Oleaginous Yeast as the Host for Fermentative Succinic Acid Production From Glucose

Engineering Oleaginous Yeast as the Host for Fermentative Succinic Acid Production From Glucose

Oleaginous yeast Yarrowia lipolytica is a prospective host for production of succinic acid. The interruption of tricarboxylic acid cycle through succinate dehydrogenase gene (SDH) deletion was reported to result in strains incapable of glucose utilization and this ability had to be restored by chemi...

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Bibliographic Details
Main Authors: Mahsa Babaei, Kanchana Rueksomtawin Kildegaard, Aligholi Niaei, Maryam Hosseini, Sirous Ebrahimi, Suresh Sudarsan, Irini Angelidaki, Irina Borodina
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
metabolic engineering
succinic acid
SDH1
Yarrowia lipolytica
fed-batch fermentation
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2019.00361/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2019.00361/full

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