In silico study of rotavirus VP7 surface accessible conserved regions for antiviral drug/vaccine design.

BACKGROUND: Rotaviral diarrhoea kills about half a million children annually in developing countries and accounts for one third of diarrhea related hospitalizations. Drugs and vaccines against the rotavirus are handicapped, as in all viral diseases, by the rapid mutational changes that take place in...

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Bibliographic Details
Main Authors: Ambarnil Ghosh, Shiladitya Chattopadhyay, Mamta Chawla-Sarkar, Papiya Nandy, Ashesh Nandy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3406019?pdf=render