PD‐L1 expression, CD8+ and CD4+ lymphocyte rate are predictive of pathological complete response after neoadjuvant chemoradiotherapy for squamous cell cancer of the thoracic esophagus

PD‐L1 expression, CD8+ and CD4+ lymphocyte rate are predictive of pathological complete response after neoadjuvant chemoradiotherapy for squamous cell cancer of the thoracic esophagus

Abstract Background Neoadjuvant chemoradiotherapy (CTRT) can effectively downstage esophageal squamous cell carcinoma (SCC) in patients with locally advanced disease and prolonged survival have been observed in patients with a pathological complete response (ypCR). Aims and methods This exploratory...

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Bibliographic Details
Main Authors: Matteo Fassan, Francesco Cavallin, Vincenza Guzzardo, Andromachi Kotsafti, Melania Scarpa, Matteo Cagol, Vanna Chiarion‐Sileni, Luca Maria Saadeh, Rita Alfieri, Ignazio Castagliuolo, Massimo Rugge, Carlo Castoro, Marco Scarpa
Format: Article
Language:English
Published: Wiley 2019-10-01
Series:Cancer Medicine
Subjects:
esophageal cancer
induction chemoradiotherapy
neoadjuvant therapy
survival analysis
squamous cell carcinoma
Online Access:https://doi.org/10.1002/cam4.2359

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https://doi.org/10.1002/cam4.2359

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