Brain MRI Reveals Ascending Atrophy in Parkinson's Disease Across Severity
Models which assess the progression of Lewy pathology in Parkinson's disease have proposed ascending spread in a caudal-rostral pattern. In-vivo human evidence for this theory is limited, in part because there are no biomarkers that allow for direct assessment of Lewy pathology. Here, we measur...
Main Authors: | Jamie C. Blair, Matthew J. Barrett, James Patrie, Joseph L. Flanigan, Scott A. Sperling, W. Jeffrey Elias, T. Jason Druzgal |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-12-01
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Series: | Frontiers in Neurology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fneur.2019.01329/full |
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