Simulating CXCR5 Dynamics in Complex Tissue Microenvironments

To effectively navigate complex tissue microenvironments, immune cells sense molecular concentration gradients using G-protein coupled receptors. However, due to the complexity of receptor activity, and the multimodal nature of chemokine gradients in vivo, chemokine receptor activity in situ is poor...

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Bibliographic Details
Main Authors: Jason Cosgrove, Kieran Alden, Jens V. Stein, Mark C. Coles, Jon Timmis
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.703088/full