Sustained Release of Antibacterial Lipopeptides from Biodegradable Polymers against Oral Pathogens.

The development of antibacterial drugs to overcome various pathogenic species, which inhabit the oral cavity, faces several challenges, such as salivary flow and enzymatic activity that restrict dosage retention. Owing to their amphipathic nature, antimicrobial peptides (AMPs) serve as the first lin...

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Bibliographic Details
Main Authors: Lea H Eckhard, Yael Houri-Haddad, Asaf Sol, Rotem Zeharia, Yechiel Shai, Shaul Beyth, Abraham J Domb, Gilad Bachrach, Nurit Beyth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5015835?pdf=render