Clinically Important Features of Porphyrin and Heme Metabolism and the Porphyrias

Clinically Important Features of Porphyrin and Heme Metabolism and the Porphyrias

Heme, like chlorophyll, is a primordial molecule and is one of the fundamental pigments of life. Disorders of normal heme synthesis may cause human diseases, including certain anemias (X-linked sideroblastic anemias) and porphyrias. Porphyrias are classified as hepatic and erythropoietic porphyrias...

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Bibliographic Details
Main Authors: Siddesh Besur, Wehong Hou, Paul Schmeltzer, Herbert L. Bonkovsky
Format: Article
Language:English
Published: MDPI AG 2014-11-01
Series:Metabolites
Subjects:
5-aminolevulinic acid
heme
iron
metalloporphyrins
mitochondria
porphobilinogen
porphyrias
porphyrins
Online Access:http://www.mdpi.com/2218-1989/4/4/977

Internet

http://www.mdpi.com/2218-1989/4/4/977

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