Functional and mutational analysis after radiation and cetuximab treatment on prostate carcinoma cell line DU145

Functional and mutational analysis after radiation and cetuximab treatment on prostate carcinoma cell line DU145

Abstract Background Epidermal Growth Factor Receptor is often overexpressed in advanced prostate carcinoma. In-vitro-studies in prostate carcinoma cell line DU145 have demonstrated increased sensibility to radiation after cetuximab treatment, but clinical data are not sufficient to date. Methods We...

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Bibliographic Details
Main Authors: Raik Schneider, Günther Gademann, Hans-Joachim Ochel, Karsten Neumann, Burkhard Jandrig, Peter Hass, Mathias Walke, Martin Schostak, Thomas Brunner, Frank Christoph
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Radiation Oncology
Subjects:
Cetuximab
Radiation
DU145
Prostate cancer
Surviving fraction
Resistance mutations
Online Access:https://doi.org/10.1186/s13014-021-01859-6

Internet

https://doi.org/10.1186/s13014-021-01859-6

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