Pharmacological Characterization of Vasorelaxant Effects of BMS-180448, a Novel Cardioselective ATP-Sensitive Potassium Channel Opener, in Rat Aorta

This study was designed to characterize vasorelaxant effects of BMS-180448 ((3S-trans)-N-(4-chlorophenyl)-N′-cyano-N″-(6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl)), a prototype cardioselective ATP-sensitive potassium channel opener, in rat aorta. BMS-180448 relaxed phenylephrine...

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Bibliographic Details
Main Authors: Yang-Su Park, Sung-Eun Yoo, Hwa-Sup Shin, Yong-Ri Jin, Yeo-Pyo Yun
Format: Article
Language:English
Published: Elsevier 2003-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319326532