Diagnostic and prognostic value of plasma neurofilament light and total-tau in sporadic Creutzfeldt-Jakob disease

Diagnostic and prognostic value of plasma neurofilament light and total-tau in sporadic Creutzfeldt-Jakob disease

Abstract Background Blood neurofilament light (Nfl) and total-tau (t-tau) have been described to be increased in several neurological conditions, including prion diseases and other neurodegenerative dementias. Here, we aim to determine the accuracy of plasma Nfl and t-tau in the differential diagnos...

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Bibliographic Details
Main Authors: Inga Zerr, Anna Villar-Piqué, Peter Hermann, Matthias Schmitz, Daniela Varges, Isidre Ferrer, Joachim Riggert, Henrik Zetterberg, Kaj Blennow, Franc Llorens
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Alzheimer’s Research & Therapy
Subjects:
Dementia
Creutzfeldt-Jakob disease
Biomarkers
Plasma
Neurofilament light
Tau
Online Access:https://doi.org/10.1186/s13195-021-00815-6

Internet

https://doi.org/10.1186/s13195-021-00815-6

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