Novel chimeric antigen receptor T cells based on T-cell receptor-like antibodies

Abstract. The need for novel therapeutics against human cancers such as leukemias and solid tumors is well recognized. Human T cells are poised to make a fundamental change in the therapeutic approach. T-cell interaction with a tumor cell is a critical event and primarily driven by T-cell receptor (...

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Bibliographic Details
Main Author: Qi Zhao
Format: Article
Language:English
Published: Wolters Kluwer Health 2019-10-01
Series:Blood Science
Online Access:http://journals.lww.com/10.1097/BS9.0000000000000032