HTLV-1-host interactions on the development of adult T cell leukemia/lymphoma: virus and host gene expressions

HTLV-1-host interactions on the development of adult T cell leukemia/lymphoma: virus and host gene expressions

Abstract Background Adult T-cell leukemia/lymphoma (ATLL) is a lymphoproliferative disorder of HTLV-1-host interactions in infected TCD4+ cells. In this study, the HTLV-1 proviral load (PVL) and HBZ as viral elements and AKT1, BAD, FOXP3, RORγt and IFNλ3 as the host factors were investigated. Method...

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Bibliographic Details
Main Authors: Hanieh Tarokhian, Hossein Rahimi, Arman Mosavat, Abbas Shirdel, Houshang Rafatpanah, Mohammad Mehdi Akbarin, Alireza Bari, Samaneh Ramezani, Seyed Abdolrahim Rezaee
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Cancer
Subjects:
HTLV-1-proviral load
HBZ
AKT1
BAD
FOXP3
RORγt
Online Access:http://link.springer.com/article/10.1186/s12885-018-5209-5

Internet

http://link.springer.com/article/10.1186/s12885-018-5209-5

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