Potential association of LMNA-associated generalized lipodystrophy with juvenile dermatomyositis

Potential association of LMNA-associated generalized lipodystrophy with juvenile dermatomyositis

Abstract Background Juvenile dermatomyositis (JDM) is an auto-immune muscle disease which presents with skin manifestations and muscle weakness. At least 10% of the patients with JDM present with acquired lipodystrophy. Laminopathies are caused by mutations in the lamin genes and cover a wide spectr...

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Main Authors: Melis Sahinoz, Shafaq Khairi, Ashley Cuttitta, Graham F. Brady, Amit Rupani, Rasimcan Meral, Marwan K. Tayeh, Peedikayil Thomas, Meredith Riebschleger, Sandra Camelo-Piragua, Jeffrey W. Innis, M. Bishr Omary, Daniel E. Michele, Elif A. Oral
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Clinical Diabetes and Endocrinology
Subjects:
Laminopathies
Myositis
LMNA
Whole exome sequencing
P.T10I
Muscle biopsy
Online Access:http://link.springer.com/article/10.1186/s40842-018-0058-3

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http://link.springer.com/article/10.1186/s40842-018-0058-3

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