The high molecular weight neurofilament subunit plays an essential role in axonal outgrowth and stabilization

The high molecular weight neurofilament subunit plays an essential role in axonal outgrowth and stabilization

Neurofilaments (NFs) are thought to provide structural support to mature axons via crosslinking of cytoskeletal elements mediated by the C-terminal region of the high molecular weight NF subunit (NF-H). Herein, we inhibited NF-H expression in differentiating mouse NB2a/d1 cells with shRNA directed a...

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Bibliographic Details
Main Authors: Sangmook Lee, Thomas B. Shea
Format: Article
Language:English
Published: The Company of Biologists 2014-09-01
Series:Biology Open
Subjects:
Neurofilament
Axonal outgrowth
Axonal stability
Nervous system development
Cytoskeleton
Online Access:http://bio.biologists.org/content/3/10/974

Internet

http://bio.biologists.org/content/3/10/974

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