2-Nitroimidazole-Furanoside Derivatives for Hypoxia Imaging—Investigation of Nucleoside Transporter Interaction, <sup>18</sup>F-Labeling and Preclinical PET Imaging

2-Nitroimidazole-Furanoside Derivatives for Hypoxia Imaging—Investigation of Nucleoside Transporter Interaction, <sup>18</sup>F-Labeling and Preclinical PET Imaging

The benefits of PET imaging of tumor hypoxia in patient management has been demonstrated in many examples and with various tracers over the last years. Although, the optimal hypoxia imaging agent has yet to be found, 2-nitroimidazole (azomycin) sugar derivatives&#8212;mimicking nucleosides&#...

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Bibliographic Details
Main Authors: Florian C. Maier, Anna Schweifer, Vijaya L. Damaraju, Carol E. Cass, Gregory D. Bowden, Walter Ehrlichmann, Manfred Kneilling, Bernd J. Pichler, Friedrich Hammerschmidt, Gerald Reischl
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Pharmaceuticals
Subjects:
tumor hypoxia
PET
small animal imaging
azomycin nucleosides
[<sup>18</sup>F]FMISO
Online Access:https://www.mdpi.com/1424-8247/12/1/31

Internet

https://www.mdpi.com/1424-8247/12/1/31

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