AAV-Anti-miR-214 Prevents Collapse of the Femoral Head in Osteonecrosis by Regulating Osteoblast and Osteoclast Activities

AAV-Anti-miR-214 Prevents Collapse of the Femoral Head in Osteonecrosis by Regulating Osteoblast and Osteoclast Activities

Osteonecrosis of the femoral head, an intractable but common disease that eventually triggers collapse of the femoral head, is characterized by increased osteoclast activity and markedly decreased osteoblast activity in the necrotic region of the femoral head. MicroRNA (miRNA)-214 (miR-214) may play...

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Bibliographic Details
Main Authors: Cheng Wang, Weijia Sun, Shukuan Ling, Yu Wang, Xin Wang, Haoye Meng, Yuheng Li, Xueling Yuan, Jianwei Li, Ruoxi Liu, Dingsheng Zhao, Qiang Lu, Aiyuan Wang, Quanyi Guo, Shibi Lu, Hua Tian, Yingxian Li, Jiang Peng
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Molecular Therapy: Nucleic Acids
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253119303075

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http://www.sciencedirect.com/science/article/pii/S2162253119303075

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