Much ado about nothing? Off-target amplification can lead to false-positive bacterial brain microbiome detection in healthy and Parkinson’s disease individuals
Abstract Background Recent studies suggested the existence of (poly-)microbial infections in human brains. These have been described either as putative pathogens linked to the neuro-inflammatory changes seen in Parkinson’s disease (PD) and Alzheimer’s disease (AD) or as a “brain microbiome” in the c...
Main Authors: | Janis R. Bedarf, Naiara Beraza, Hassan Khazneh, Ezgi Özkurt, David Baker, Valeri Borger, Ullrich Wüllner, Falk Hildebrand |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-03-01
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Series: | Microbiome |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40168-021-01012-1 |
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